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AIM To prospectively evaluate the efficacy of submucosal injection of platelet-rich plasma(PRP)on endoscopic resection of large sessile lesions.METHODS Eleven patients were submitted to endoscopic mucosal resection(EMR)with prior injection of PRP,obtained at the time of endoscopy.Patients were followed during 1 mo.The incidence of adverse events(delayed bleeding or perforation)and the percentage of mucosal healing(MHR)after 4 wk were registered.RESULTS EMR was performed in 11 lesions(46.4 mm±4 mm,range 40-70 mm).Delayed bleeding or perforation was not observed in any patient.Mean ulcerated area at baseline was 22.7 cm2±11.7 cm2 whereas at week 4 were 2.9 cm2±1.5 cm2.Patients treated with PRP showed a very high MHR after 4 wk(87.5%).CONCLUSION PRP is an easy-to-obtain solution with proven and favourable biological activities that could be used in advanced endoscopic resection.
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篇名 Submucosal injection of platelet-rich plasma in endoscopic resection of large sessile lesions
来源期刊 世界胃肠内镜杂志:英文版(电子版) 学科 医学
关键词 Platelet-rich plasma endoscopic MUCOSAL RESECTION SUBMUCOSAL injection LARGE LESIONS
年,卷(期) 2018,(11) 所属期刊栏目
研究方向 页码范围 348-353
页数 6页 分类号 R
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节点文献
Platelet-rich
plasma
endoscopic
MUCOSAL
RESECTION
SUBMUCOSAL
injection
LARGE
LESIONS
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研究去脉
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世界胃肠内镜杂志:英文版(电子版)
月刊
1948-5190
北京市朝阳区东四环中路62号楼远洋国际中
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557
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