Evaluation of Early Warning Indicators of ARV Resistance to HIV in the Hospital of Tivaouane from 2008 to 2016

• 作者: Agbogbenkou Tévi Déla-dem Lawson Bernard Marcel Diop Haby Dione Mamadou Ba Ndeye Astou Lakhe Ndeye Biram Niang Papa Souleymane Toure Sylvie Audrey Diop-Nyafouna
• 来源期刊: 传染病进展(英文)
• 学科: 医学
• 关键词: HIV RESISTANCE EWI Tivaouane
• 年，卷（期）: 2018,（2）
• 页码范围: 54-63
• 页数: 10页
• 分类号: R73

摘要

Introduction: HIV resistance to antiretroviral is currently a global concern, and requires increased surveillance in a context of widespread ARV treatment. Objective: To evaluate early warning indicators of HIV resistance to ARVs in the Hospital of Tivaouane (Senegal) where viral load was not routinely available. Methods: This is a cross-sectional retrospective study from 2008-2016. The etraction tool (May 2010 version) was used to analyze the EWI. Results: We collected 360 HIV positive patients followed on average for 3.57 years ± 3.02. 2009, 2010 and 2012 recorded 100% ARV prescribing rates. Throughout the study period, the percentage of patients lost to follow-up during the first 12 months of treatment was less than 20%. Virtually, all patients were still under primary ARVT over 12-month treatment. All patients (100%) withdrew their ARV drugs on time. No stock storage regarding various classes of ARVs was noted during the study period. Conclusion: At the end of this study we recommend to maintain regular follow-up of EWI, and combine it with the achievement of viral load.