Fabrication of three-dimensional proteinaceous micro-and nano-structures by femtosecond laser cross-linking

• 来源期刊: 光电进展（英文版）
• 年，卷（期）: 2018,（4）
• 页码范围: 12-29
• 页数: 18页
• 语种: 中文
• DOI: 10.29026/oea.2018.180008

摘要

Proteins are a class of biomaterials having a vast array of functions,including the catalysis of metabolic reactions,DNA replication,stimuli response and transportation of molecules.Recent progress in laser-based fabrication technologies has enabled the formation of three-dimensional (3D) proteinaceous micro-and nano-structures by femtosecond laser cross-linking,which has expanded the possible applications of proteins.This article reviews the current knowledge and recent advancements in the femtosecond laser cross-linking of proteins.An overview of previous studies related to fabrication using a variety of proteins and detailed discussions of the associated mechanisms are provided.In addition,advances and applications utilizing specific protein functions are introduced.This review thus provides a valuable summary of the 3D micro-and nano-fabrication of proteins for biological and medical applications.