Amplitude-Integrated Electroencephalography Predicts Outcome in Patients with Coma After Acute Brain Injury

• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2018,（4）
• 页码范围: 639-646
• 页数: 8页
• 语种: 英文

摘要

Prognostication of coma patients after brain injury is important,yet challenging.In this study,we evaluated the predictive value of amplitude-integrated electroencephalography (aEEG) for neurological outcomes in coma patients.From January 2013 to January 2016,128 coma patients after acute brain injury were prospectively enrolled and monitored with aEEG.The 6-month neurological outcome was evaluated using the Cerebral Performance Category Scale.aEEG monitoring commenced at a median of 7.5 days after coma onset.Continuous normal voltage predicted a good 6-month neurological outcome with a sensitivity of 93.6％ and specificity of 85.2％.In contrast,continuous extremely low voltage,burst-suppression,or a flat tracing was correlated with poor 6-month neurological outcome with a sensitivity of 76.5％ and specificity of 100％.In conclusion,aEEG is a promising predictor of 6-month neurological outcome for coma patients after acute brain injury.