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摘要:
Introduction: Gastrointestinal stromal tumor (GIST) is the most common non-epithelial, mesenchymal tumor of the digestive tract. Targeted therapy has improved the prognosis but the diagnosis must be accurate before using the existing drugs. Aim: To report the diagnostic difficulty in our context through the clinical polymorphism and define the position of targeted therapy in the management of GIST metastatic stomach. Casuistry: We report 3 cases of gastric GIST with liver metastasis in different circumstances of discovery. Patients were 21, 45, and 73 years old. Discovery circumstances were respectively digestive hemorrhage, severe clinical anemia, abdominal tumor and gastric tumor. There was hepatic metastasis in the three cases. The three patients received Imatinib treatment, adjuvant treatment for the first two cases, and neo-adjuvant treatment for the third case, with a very good clinical response and CT response on metastases. Conclusion: Because of their rarity, GISTs are often difficult to diagnose, and necessarily require immunohistochemistry which is not available in our work context. The effectiveness of targeted therapy even on metastasis needs a rigorous diagnostic approach to improve patient survival.
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篇名 Hepatic Metastatic GIST: Diagnostic and Therapeutic Difficulties in Souro Sanou Teaching Hospital in Bobo Dioulasso, Burkina Faso
来源期刊 肠胃病学期刊(英文) 学科 医学
关键词 Gastric STROMAL Tumors METASTASES IMATINIB Surgery Bobo Dioulasso
年,卷(期) 2018,(12) 所属期刊栏目
研究方向 页码范围 455-462
页数 8页 分类号 R73
字数 语种
DOI
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Gastric
STROMAL
Tumors
METASTASES
IMATINIB
Surgery
Bobo
Dioulasso
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研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
肠胃病学期刊(英文)
月刊
2163-9450
武汉市江夏区汤逊湖北路38号光谷总部空间
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108
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0
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0
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