Adherence to pharmacological and non-pharmacological treatment of frail hypertensive patients

• 来源期刊: 老年心脏病学杂志（英文版）
• 年，卷（期）: 2018,（2）
• 页码范围: 153-161
• 页数: 9页
• 语种: 英文
• DOI: 10.11909/j.issn.1671-5411.2018.02.002

摘要

Objeetive To investigate the relationship between frailty syndrome (FS) and adherence to pharmacological and non-pharmacological treatment for hypertension.Methods The study included 100 patients diagnosed with hypertension and treated with one or more hypotensive drugs.Results Frail patients obtained low scores (4.1 ± 2.0) for adherence to pharmaceutical treatment of hypertension,while non-frail patients obtained moderate scores (6.1 ± 2.1).Non-frail patients had higher scores in two out of four domains of the Health Behavior Inventory (HBI):positive mental attitudes (3.6 ± 0.4 vs.3.2 ± 0.5;P =0.006) and health practices (3.6 ± 0.5 vs.3.2 ± 0.5;P ＜ 0.03);as well as higher global scores (HBI raw score):83.3 ± 10.6 vs.77.3 ± 9.5;P ＜ 0.03.Multiple regression analysis showed that frailty syndrome (FS)was a statistically significant independent determinant of worse adherence to pharmacological treatment (β =-0.27;P ＜ 0.001) and health behaviors (β =-0.10;P =0.036).Education was a statistically significant independent determinant of better adherence to pharmacological treatment (β =0.82;P =0.012),while net income positively affected health behaviors as measured by the HBI (β =0.39;P =0.046).Conclusions FS is a significant independent factor contributing to worse adherence to pharmacological and non-pharmacological treatment of hypertension.Better education significantly improves patients' adherence to the prescribed pharmacological treatment,while a good financial standing evidenced by high net income is a detenninant of better adherence to health-related behaviors recommended in hypertension treatment.