Deadlier than the malate

• 来源期刊: 细胞研究（英文版）
• 年，卷（期）: 2018,（6）
• 页码范围: 609-610
• 页数: 2页
• 语种: 英文

摘要

Plant and animal cells share similar malate-mediated cell death processes,but plants have evolved a unique intracellular communication between organelles in regulating programmed cell death in response to specific photoperiods. Malate (malic acid) is made by all organisms.In plants,malate contributes to the pleasant taste in sour fruits.However,in a recent paper published in Cell Research,Zhao et al.1 reported a novel role of malate in cell death of both plants and animals.It is the first report that the malate transfer from chloroplasts (the plant-specific photosynthetic organelle) to mitochondria can lead to cell death under continuous light.