Significant Spike-Specific IgG and Neutralizing Antibodies in Mice Induced by a Novel Chimeric Virus-Like Particle Vaccine Candidate for Middle East Respiratory Syndrome Coronavirus

• 来源期刊: 中国病毒学
• 年，卷（期）: 2018,（5）
• 页码范围: 453-455
• 页数: 3页
• 语种: 英文

摘要

Dear Editor, Middle East respiratory syndrome coronavirus (MERS-CoV),first isolated in 2012,has emerged zoonotically among humans (van Boheemen et al.2012).Since then,MERS-CoV continues to be a public health concern,with a fatality rate of 35％.On-going MERS-CoV outbreaks highlight the urgent need for the development of interventional measures,including an effective vaccine against MERS-CoV infection.Currently,no licensed therapeutic or vaccine is available (Okba et al.2017).