Evaluation of Antibody-Dependent Enhancement of SARS-CoV Infection in Rhesus Macaques Immunized with an Inactivated SARS-CoV Vaccine

• 来源期刊: 中国病毒学
• 年，卷（期）: 2018,（2）
• 页码范围: 201-204
• 页数: 4页
• 语种: 英文

摘要

Dear Editor, In 2003,severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in Guangdong Province,China,infected more than 8000 individuals,and resulted in a 10％ mortality rate (Rota et al.2003).Later,in 2012,a novel CoV,Middle East respiratory syndrome coronavirus (MERS-CoV),was isolated from the sputum of a man in Saudi Arabia (Perl et al.2014).Notably,MERS-CoV recently reemerged in the Republic of Korea,and killed 36 out of 186 confirmed cases (Korea Centers for Disease Control and Prevention 2015).Therefore,SARS-CoV still carries the potential for resurgence;efforts are being made to prevent the recurrence of an epidemic.