With the support by the National Natural Science Foundation of China,the research team led by Prof.Kuang Hua (匡华) from the State Key Laboratory of Food Science and Technology,International Joint Research Laboratory for Bio interface and Bio detection,Jiangnan University,discovered that the truncated morphology semiconductor nanocrystals could work mimetically as restricted incision enzyme to cut the specific site of DNA sequence.The work was published in Nature Chemistry (2018,10:821-830).