Visible-light-mediated photocatalysis as a new tool for catalytic asymmetric dearomatization (CADA) reactions

• 来源期刊: 科学通报（英文版）
• 年，卷（期）: 2018,（13）
• 页码范围: 809-811
• 页数: 3页
• 语种: 英文

摘要

Aromatic compounds often serve as widely available and fundamental synthetic materials in polymers,paints,cosmetics,and pharmaceuticals.The development of novel transformations based on simple aromatics to access highly value-added structures is in great demand.In this regard,catalytic asymmetric dearomatization (CADA) reactions can convert planar aromatic compounds into enantio-enriched three-dimensional cyclic molecules (Scheme 1) [1,2].The past several years have witnessed significant progress in CADA reactions and a large number of strategies have been developed.These reported methods include oxidative dearomatization reactions,dearomatization by hydrogenation,dearomatization by Diels-Alder and related reactions,allylic arylative,and Heck-type dearomatization,Reissert-type dearomatization,etc.Among these methods,dearomatizaton is generally initiated by thermal-activated processes.