Identification of Abnormal 51 CTA/CTG Expansion as Probably the Shortest Pathogenic Allele for Spinocerebellar Ataxia-8 in China

• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2018,（5）
• 页码范围: 859-862
• 页数: 4页
• 语种: 英文

摘要

Dear Editor, Spinocerebellar ataxias (SCAs) are a group of genetic disorders characterized by slowly progressive incoordination of gait and are often associated with poor coordination of the hands,speech,and eye movements.Frequently,atrophy of the cerebellum occurs.The genetic forms of ataxia are diagnosed by family history,physical examination,neuroimaging,and molecular genetic testing.