Oxidation-induced ortho-selective C-H bond functionalization of 2-naphthylamine derivative

• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2018,（10）
• 页码范围: 1274-1277
• 页数: 4页
• 语种: 英文

摘要

Selective C-H bond functionalization has been emerged as a versatile strategy for the construction of new chemical bonds.In the past decades,the directing group (DG)-assisted C-H bond activation has been developed as one of the most efficient methods for selective C-H functionalization.Although a great progress has been made by utilizing this traditional method,developing new strategy for selective C-H bond functionalization is still highly demanded.Hence,a novel oxidation-induced C-H bond functionalization method was demonstrated in this work.By this new method,ortho-C(sp2)-H chlorination of N-substituted 2-naphthylamine was realized in a highly selective manner.