Integrating NIR light photocage enables in vivo dual-channel tracking of drug release

• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2018,（11）
• 页码范围: 1347-1348
• 页数: 2页
• 语种: 英文

摘要

On-demand drug release at the right place and time becomes a central challenge in disease diagnosis and therapy.Light is a uniquely powerful tool to manipulate a biological process in space or time.Light-triggered drug delivery systems (DDSs) have proven to be an effective strategy for improving therapeutics.These caged prodrugs are functional light-sensitive probes that make the drug in an inactive form by covalent conjugation.Light irradiation liberates the caged drugs,permitting facile control intact and activate prodrugs in space and time.