Anatase TiO2 nanosheets (-ns-) with dominant exposed {001} facets were used as support to load copper,and the synthesized Cu/TiO2-ns catalysts were evaluated for CO2 hydrogenation to methanol.Under the reaction conditions,P=3.0MPa,T=260 ℃,V(N2)∶V(H2)∶V(CO2)=8∶69∶23 and gas hourly space velocity (GHSV)=3600 mL g 1 h-1,the methanol yield reached an appealing high value,5.6%.Copper-loading amount,calcination temperature and reduction atmosphere have been investigated in this work,which significantly influence the particle sizes of copper and/or the defect concentration in TiO2,then leading to different catalytic performance.Characterizations of XRD,EPR,CO2-TPD and FTIR demonstrate that higher specific surface area of Cu is good for the hydrogenation of CO2 and adequate amount of Ti3+ plays important roles in CO2 activation.Both of them facilitate high turnover frequency (TOF) of methanol formation.