Progress in Single Cell Sequencing Technology

• 作者: Heping Pan Na Ye Ping Yan Qicai Ma Wenli Wu Xingdong Wang
• 来源期刊: 动物研究(英文)
• 学科: 教育
• 关键词: SINGLE CELL isolation SINGLE CELL SEQUENCING WHOLE GENOME TRANSCRIPTOME
• 年，卷（期）: 2019,（1）
• 页码范围: 20-26
• 页数: 7页
• 分类号: G63

摘要

Cells are the basic unit of life structure and life activities.Because of the complex micro-environment of cells,the content of components that play a key role is relatively small,so single-cell analysis is extremely challenging.In recent years,single-cell sequencing technology has been developed and matured.Single-cell sequencing can reveal the composition and physiological diversity of cells,and the existing single-cell separation technology,single-cell whole genome amplification technology,single The principles and applications of cell whole transcriptome amplification technology and single cell transcriptome sequencing are summarized and summarized.