Role of tumor-associated immune cells in prostate cancer: angel or devil?

• 来源期刊: 亚洲男性学杂志（英文版）
• 年，卷（期）: 2019,（5）
• 页码范围: 433-437
• 页数: 5页
• 语种: 英文
• DOI: 10.4103/aja.aja_47_19

摘要

Prostate cancer is the most common malignancy in the reproductive system of older males.Androgen deprivation therapy (ADT)is an important treatment for prostate cancer patients.However,almost all prostate cancer patients unavoidably progress to the castration-resistant stage after ADT treatment.Recent studies have shown that tumor-associated immune cells play major roles in the initiation,progression,and metastasis of prostate cancer.Various phenotypes of tumor-associated immune cells have tumor-promoting or antitumor functions mediated by interacting with tumor cells.Here,we review the current knowledge of tumorassociated immune cells in prostate cancer.