Synthesis of Some New Thioethers and 4-Thiazolidinones Bearing 3-(Pyridine-4'-yl)-1,2,4-Triazino[5,6-<i>b</i>]Indole Moiety as Antifungal Agents

• 作者: Wafa A. Baker Bawazir
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: THIOETHERS Thiazolidnones 1 2 4-Triazino INDOLE FUNGICIDAL Cycloaddition
• 年，卷（期）: yjhxgjqkyw_2019,（1）
• 页码范围: 37-46
• 页数: 10页
• 分类号: O6

摘要

Some new asymmetric thioethers 5 and 4-thiazolidinones 6 have been obtained from condensation of 5-formyl-3-(pyridin-4'-yl)-1,2,4-triazino[5,6-b] indole (3) with halogenated aromatic amines followed by addition of thiophenol and/or cycloaddition with thiolactic acids in nonpolar solvents. Structures of the products confirmed by elemental analysis and spectral measurements. The new systems obtained were evaluated as antifungal agents.