Synthesis of Novel Heteropolycyclic Nitrogen Systems Bearing Fluorine Substituted Pyrazolo[3,4-d] Pyrimidine Derived from Polyfunctional π-Acceptor Compounds and Guanidine as Fungicidal Probes

• 作者: Dina A. Bakhotmah Salwa Y. Al-Hazme
• 来源期刊: 有机化学国际期刊(英文)
• 学科: 化学
• 关键词: Synthesis Polyheterocyclic Pyrazolo[3 4-d] PYRIMIDINE ANTIFUNGAL
• 年，卷（期）: yjhxgjqkyw_2019,（1）
• 页码范围: 73-83
• 页数: 11页
• 分类号: O6

摘要

Novel heteropolycyclic nitrogen systems bearing fluorine substituted pyrazolo[3,4-d] pyrimidine moiety have been synthesis by the interaction between N’-heteroaryl guanidine 4 with polyfunctional π-acceptors in different media and condition. The structures of the synthesis compounds were established by spectroscopic analysis and evaluated as antifungal probes in various concentration.