Four Cousins with Hypospadias, Is It Familial or Environmental? (Case Report)

• 作者: Mina Senada Mohamed Ahmed Hassan Mohamed Elsayed Mohamed Mohamed Yousef Abdalazeem
• 来源期刊: 现代整形外科(英文)
• 学科: 医学
• 关键词: HYPOSPADIAS FAMILIAL ENVIRONMENTAL SNODGRASS REPAIR
• 年，卷（期）: 2019,（3）
• 页码范围: 59-63
• 页数: 5页
• 分类号: R73

摘要

Hypospadias is one of the most common birth defects. However, its etiology remains largely unknown. Genetic and also intrauterine environmental factors have a principal role in causing familial hypospadias. Hypospadias repair is done through several techniques, one of which is Snodgrass technique which has many advantages. The 4 cousins underwent repair with no complications during 6 months follow up period. Methods: Urethroplasty using Snodgrass hypospadias repair of 4 cousins with positive parental consanguinity and absent family history of hypospadias. Results: 4 cousins underwent Snodgrass (Tubularized incised plate urethroplasty) with no complications after 6 months follow up. Conclusion: Although there is high heritability of hypospadias that also aggregates within second- and third-degree relatives, environmental factors may play a principal role in causing familial hypospadias. Hypospadias repair has a long learning curve. The continuous auditing should be done to improve the results.