Radiofrequency and malignant biliary strictures:An update

• 作者: Alessandro Repici Benedetto Mangiavillano Francesco Auriemma Luca De Luca Mario Bianchetti
• 来源期刊: 世界胃肠内镜杂志:英文版(电子版)
• 学科: 医学
• 关键词: RADIOFREQUENCY Ablation Endoscopic RETROGRADE colangiopancreatography MALIGNANT BILIARY STRICTURES
• 年，卷（期）: 2019,（2）
• 页码范围: 95-102
• 页数: 8页
• 分类号: R

摘要

Malignant biliary strictures are usually linked to different types of tumors,mainly cholangiocarcinoma,pancreatic and hepatocellular carcinomas.Palliative measures are usually adopted in patients with nonresectable or borderline resectable biliary disease.Stent placement is a well-known and established treatment in patients with unresectable malignancy.Intraductal radiofrequency ablation(RFA)represents a procedure that involves the use of a biliary catheter device,via an endoscopic approach.Indications for biliary RFA described in literature are:Palliative treatment of malignant biliary strictures,avoiding stent occlusion,ablating ingrowth of blocked metal stents,prolonging stent patency,ablating residual adenomatous tissue after endoscopic ampullectomy.In this mini-review we addressed focus on technical success defined as deployment of the RF catheter,virtually succeeded in all patients included in the studies.About efficacy,three main outcome measures have been contemplated:Biliary decompression and stent patency,survival.Existing studies suggest a beneficial effect on survival and stent patency with RFA,but current impression is limited because most of studies have been performed using a retrospective design,on diminutive and dissimilar cohorts of patients.