Molecular basis of fever boosting immune cell trafficking
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摘要:
With the support by the National Natural Science Foundation of China,the National Basic Research Program of China,the Chinese Academy of Sciences,and the China Postdoctoral Science Foundation,the research team led by Prof.Chen JianFeng (陈剑峰) at Shanghai Institute of Biochemistry and Cell Biology of Chinese Academy of Sciences,uncovers a mechanism to explain how fever promotes T lymphocyte trafficking and enhances immune surveillance during infection through a thermal sensory heat shock protein 90 (Hsp90)-α4 integrin pathway,which was published in Immunity (2019,50:137-151).