Energy coupling mechanism of F0 in a rotary ATP synthase: a model update
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摘要:
INTRODUCTION
In nearly all living cells,rotary ATP synthases of the F1F0 family are essential to inter-conversing of energy between the transmembrane electrochemical potential and the ATP form (Boyer 1997).During ATP synthesis,the Fo sector of the ATP synthase machinery converts the electrochemical energy of either protons or sodium ions into mechanical energy of a rotor;in turn,this energy is converted into chemical energy of ATP by the F1 sector (Gruber et al.2014;Nakamoto et al.2008).