How TP53 (almost) became an oncogene

• 作者: Robert A.Weinberg
• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2019,（7）
• 页码范围: 531-533
• 页数: 3页
• 语种: 英文
• DOI: 10.1093/jmcb/mjz061

摘要

Like the histories of many other genes, the discovery and characterization of p53 are associated with some false leads,dead ends, and major detours.The chronicle of p53's early years is no exception.As is now well known, the protein was actually discovered independently by three groups-those of Arnie Levine,David Lane, and Lloyd Old.