p53: not just a tumor suppressor

• 作者: Moshe Oren
• 来源期刊: 分子细胞生物学报（英文版）
• 年，卷（期）: 2019,（7）
• 页码范围: 539-543
• 页数: 5页
• 语种: 英文
• DOI: 10.1093/jmcb/mjz070

摘要

Nowadays, p53 is like a Dreamliner airplane, riding the high skies of cancer research with dignity and pride.You do not have to be a card-bearing p53 researcher to know about p53, care about it, and respect it.Yet, this was not always so.As a matter of fact, in the first years of p53 research, from its discovery in the late 1970's to about the end of the 1980's,p53 was more like a kite: one moment high up in the air, the next moment being dragged on the ground.