Association of Genetic Polymorphisms with Age at Onset in Han Chinese Patients with Bipolar Disorder

• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2019,（4）
• 页码范围: 591-594
• 页数: 4页
• 语种: 英文

摘要

Dear Editor, Bipolar disorder (BD) is a chronic and disabling disorder characterized by manic,hypomanic,or depressive episodes,with an estimated lifetime prevalence ranging from 1％ to 5％.Globally,it is a leading cause of disability and a socioeconomic burden.Gene-environment interactions are thought to be involved in the neurobiology of BD,with genetic factors contributing to 60％-85％ of BD patients.