Application of Ultrahigh Doses of Morphine in Systemic Multiple Epithelioid Hemangioendothelioma without Addiction: A Case Report

• 作者: Mingfei Ma Minqiang Liu Renliang He Xinzhong Ning
• 来源期刊: 临床医学病理报告(英文)
• 学科: 医学
• 关键词: EPITHELIOID HEMANGIOENDOTHELIOMA MORPHINE PAIN ADDICTION
• 年，卷（期）: lcyxblbgyw_2019,（11）
• 页码范围: 285-294
• 页数: 10页
• 分类号: R96

摘要

Morphine is a potent opioid which is commonly used for relieving cancer pain with strong analgesic properties. Epithelioid hemangioendothelioma (EHE), a rare vascular tumor that can cause severe chronic pain, is usually diagnosed in a surgical biopsy. We describe ultrahigh doses of morphine used in a case of a 17-year-old male who suffered from severe chest pain with systemic multiple EHE. The total dosage of morphine was as high as 92,530 mg given within 164 days. However, we observed no indications that the patient was addicted.