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Primary cutaneous gamma-delta T-cell lymphoma (PCGD-TCL) is a very uncommon and extremely aggressive tumor, and is described in the newly re-vised World health organization for research and treatment of cancer classification of cutaneous lymphomas. A 43-year-old male patient presented with a 4 months history of cutaneous lesion over upper lip, without plaque and any constitutional symptom. Histopathological examination of skin biopsy revealed infiltration of atypical lymphocytes with hyperchromatic irregular nuclei. Immunophenotyping pattern of skin biopsy was compatible with PCGD-TLC. It is a highly aggressive tumor resistant to chemotherapy, immunotherapy, and radiation therapy. The GDTCL is characterized by a worse prognosis with a median survival of 15 months. Early diagnosis is essential and aggressive therapy is necessary.
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篇名 Primary Cutaneous Gamma Delta T Cell Lymphoma: A Clinicopathological Analysis
来源期刊 生物科学与医学(英文) 学科 医学
关键词 CUTANEOUS Gamma-Delta T-CELL LYMPHOMA HEMATOXYLIN and EOSIN IMMUNOHISTOCHEMISTRY
年,卷(期) 2019,(5) 所属期刊栏目
研究方向 页码范围 22-26
页数 5页 分类号 R73
字数 语种
DOI
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研究主题发展历程
节点文献
CUTANEOUS
Gamma-Delta
T-CELL
LYMPHOMA
HEMATOXYLIN
and
EOSIN
IMMUNOHISTOCHEMISTRY
研究起点
研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
生物科学与医学(英文)
月刊
2327-5081
武汉市江夏区汤逊湖北路38号光谷总部空间
出版文献量(篇)
721
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0
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0
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