Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia
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摘要:
With the support of the National Natural Science Foundation of China and the Chinese Academy of Sciences,the laboratory led by Yang CaiGuang (杨财广) from Shanghai Institute of Materia Medica,Chinese Academy of Sciences,has identified a potential therapeutic small molecule for treating the acute myeloid leukemia (AML) by targeting the oncogenic RNA demethylase FTO,which was published in CancerCell (2019,35:677-691).