Visible light promoted synthesis of N-aroylsulfoximines by oxidative C-H acylation of NH-sulfoximines

• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2019,（9）
• 页码范围: 1213-1220
• 页数: 8页
• 语种: 英文

摘要

The visible light-promoted synthesis of N-aroylsulfoximines has been accomplished via an oxidative dehydrogenative coupling at room temperature under air without the addition of a photosensitizer,metal catalyst,or base.This process exhibits good functional group tolerance,allows facile isolation and purification,and affords N-aroylsulfoximines with high efficiency.The efficiency of the newly developed protocol is described in detail with 27 examples with yields ranging from 80％ to 96％.Furthermore,the chirality of the NH-sulfoximine is completely maintained in the desired N-aroylsulfoximine product (＞99％ ee).