Copper catalyzed/mediated direct B-H alkenylation/alkynylation in carboranes

• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2019,（1）
• 页码范围: 74-79
• 页数: 6页
• 语种: 英文

摘要

Base metal catalyzed regioselective cage B-H functionalization has been achieved.Under the assistance ofa bidentate directing group,Cu-catalyzed [4+2] annulation of carboranyl amides with internal alkynes affords unprecedented C,B-substituted carborane-fused-pyridone derivatives,whereas the use of terminal alkynes leads to B-H/C(sp)-H dehydrocoupling products.The isolation and structural identification of a notably stable Cu(I) intermediate shed light on the reaction mechanism,which is proposed to involve a Cu(Ⅲ) intermediate.