Synthesis of 4H-chromenes by silver (I)-catalyzed cycloaddition of ortho-quinone methides with N-allenamides
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摘要:
Chromenes represent an important class of six-membered heterocycles and have drawn tremendous attention in recent years.In this article,we report a convenient and practical synthesis of this heterocycle by a silver (I)-catalyzed cycloaddition reaction between in situ generated ortho-quinone methides and N-allenamides.Diverse 4H-chromenes were synthesized in good to excellent yields under very mild conditions.