Engineered nanoparticles circumvent the adaptive treatment tolerance to immune-checkpoint blockade therapy

• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2019,（12）
• 页码范围: 1557-1560
• 页数: 4页
• 语种: 英文

摘要

The fight against cancer has witnessed the rapid development of various therapeutic methodologies,including chemotherapy,surgery,radiotherapy,phototherapy,and the emerging immunotherapy [1].However,malignancies evolve adaptive tolerance under the threatening conditions upon therapies because of some potential biological or genetic mutations,which may cause serious adverse events,compromised therapeutic efficacy and even treatment failure.