Nickel-catalyzed reductive coupling of glucosyl halides with aryl/vinyl halides enabling β-selective preparation of C-aryl/vinyl glucosides

• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2019,（11）
• 页码范围: 1492-1496
• 页数: 5页
• 语种: 英文

摘要

This work describes stereoselective preparation of β-C-aryl/vinyl glucosides via mild Ni-catalyzed reductive arylation and vinylation of C1-glucosyl halides with aryl and vinyl halides.A broad range of aryl halides and vinyl halides were employed to yield C-aryl/vinyl glucosides in 42％-93％ yields.Good to excellent β-selectivities were obtained for C-glucosides by using tridentate ligand.