Photocatalytic decarboxylative coupling between α-oxocarboxylicacids and alkenes

• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2019,（11）
• 页码范围: 1497-1500
• 页数: 4页
• 语种: 英文

摘要

Photocatalytic decarboxylative cross-coupling which achieves the derivatization of widespread organic acids has become a hot topic in organic synthesis.As special acids,α-oxocarboxylicacids show the great potential in running decarboxylation to construct ketone derivatives.In this article,we have developed a photocatalytic decarboxylative cross-coupling of α-oxocarboxylic acids and olefins to the synthesis of diverse aryl ketones.Various alkenes and α-oxocarboxylicacids were compatible,generating the desired products in up to 90％ yield.Preliminary mechanism studies suggest that a free radical pathway is involved in this process.