Silver-catalyzed three-component reaction: synthesis of N2-substituted 1,2,3-triazoles via direct benzylic amination

• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2019,（8）
• 页码范围: 1001-1006
• 页数: 6页
• 语种: 英文

摘要

A novel Ag(I)-catalyzed benzylic amination reaction with in situ generation of NH-1,2,3-triazoles for N2-substituted 1,2,3-triazole scaffolds is described.This protocol is achieved with easily accessible substrate,broad functional group,good regioselectivity,thus providing the efficient and practical method to diverse N2-substituted 1,2,3-triazole rings with moderate to good yields.