The effect of fatigue on brain connectivity networks

• 作者: Jingnan Sun Shangen Zhang Xiaorong Gao
• 来源期刊: 神经科学(英文)
• 学科: 医学
• 关键词: FATIGUE brain connection analysis steady-state visual evoked potential(SSVEP) noise rapid serial visual presentation
• 年，卷（期）: sjkxyw,（2）
• 页码范围: 120-131
• 页数: 12页
• 分类号: R741.02

摘要

In the fatigue state,the neural response characteristics of the brain might be different from those in the normal state.Brain functional connectivity analysis is an effective tool for distinguishing between different brain states.For example,comparative studies on the brain functional connectivity have the potential to reveal the functional differences in different mental states.The purpose of this study was to explore the relationship between human mental states and brain control abilities by analyzing the effect of fatigue on the brain response connectivity.In particular,the phasescrambling method was used to generate images with two noise levels,while the N-back working memory task was used to induce the fatigue state in subjects.The paradigm of rapid serial visual presentation(RSVP)was used to present visual stimuli.The analysis of brain connections in the normal and fatigue states was conducted using the open-source e Connectome toolbox.The results demonstrated that the control areas of neural responses were mainly distributed in the parietal region in both the normal and fatigue states.Compared to the normal state,the brain connectivity power in the parietal region was significantly weakened under the fatigue state,which indicates that the control ability of the brain is reduced in the fatigue state.