Kidney injury in COVID-19

• 作者: Adeel Rafi Ahmed Chaudhry Adeel Ebad Muniza Manshad Satti Peter J Conlon Sinead Stoneman
• 来源期刊: 世界肾病学杂志:英文版
• 学科: 医学
• 关键词: COVID-19 SARS-CoV-2 Acute kidney injury Cytokine storm Acute respiratory distress syndrome Renal replacement therapy
• 年，卷（期）: 2020,（2）
• 页码范围: 18-32
• 页数: 15页
• 分类号: R69

摘要

Coronavirus disease 2019(COVID-19)continues to affect millions of people around the globe.As data emerge,it is becoming more evident that extrapulmonary organ involvement,particularly the kidneys,highly influence mortality.The incidence of acute kidney injury has been estimated to be 30%in COVID-19 non-survivors.Current evidence suggests four broad mechanisms of renal injury:Hypovolaemia,acute respiratory distress syndrome related,cytokine storm and direct viral invasion as seen on renal autopsy findings.We look to critically assess the epidemiology,pathophysiology and management of kidney injury in COVID-19.