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摘要:
This work is describing a thionization method for glycosyl urea and carbamide of sugars by using the Lawesson’s reagent. It is proposed the method based on the interaction of glycosyl urea and carbamide of sugars with the Lawessons reagent at a 1:1 ratio in the presence of a pyridine. As a result, sulfur-containing derivatives of sugar carbamides are obtained with the help of Lawesson’s reagent. Obtained experimental data are indicating the developed new method for thionization of sugar carbamides, which opens up broad possibilities for synthesis of various carbohydrate derivatives of thiourea. Significance of this work is that, thiourea derivatives are promising bactericidal, fungicidal and anti-inflammatory drugs. Therefore, the preparation of thiourea derivatives and the study of their properties remain topical tasks in the field of chemistry.
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篇名 Thionization Method of Glycosyl Urea and Carbamide Sugars
来源期刊 有机化学国际期刊(英文) 学科 化学
关键词 Glycosyl Urea Glycosyl Thiourea Synthesis Lawesson’s Reagent ANTI-INFLAMMATORY BACTERICIDAL Fungicidal Properties
年,卷(期) 2020,(3) 所属期刊栏目
研究方向 页码范围 111-122
页数 12页 分类号 O62
字数 语种
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节点文献
Glycosyl
Urea
Glycosyl
Thiourea
Synthesis
Lawesson’s
Reagent
ANTI-INFLAMMATORY
BACTERICIDAL
Fungicidal
Properties
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研究来源
研究分支
研究去脉
引文网络交叉学科
相关学者/机构
期刊影响力
有机化学国际期刊(英文)
季刊
2161-4687
武汉市江夏区汤逊湖北路38号光谷总部空间
出版文献量(篇)
303
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0
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0
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