Angiosarcomatous component in gliosarcoma: case report and consideration of diagnostic challenge and hemorrhagic propensity

• 来源期刊: 生物医学研究杂志（英文版）
• 学科: 医学
• 年，卷（期）: 2020,（2）
• 页码范围: 143-148
• 页数: 6页
• 分类号: R739.41
• 语种: 英文

摘要

An angiosarcomatous component in gliosarcoma may be associated with an increased intraoperative hemorrhagic risk and preoperative diagnostic challenge.We report a unique case of gliosarcoma with an angiosarcomatous component in a 61-year-old man.His brain MRI demonstrated a well-demarcated right occipital tumor with multiple flow voids and rim-like enhancement as well as intratumoral strip and nodular enhancements.He underwent a craniotomy for tumor resection.Intraoperatively,significant tumor hemorrhage required greater efforts to control intraoperative bleeding and to maintain hemostasis.Pathological examination of the tumor revealed alternating gliomatous and sarcomatous/angiosarcomatous components with intratumoral hemorrhage.He was postoperatively treated with chemoradiation.The tumor recurred at 9 months,for which the second resection was performed with similarly greater efforts to achieve hemostasis.The recurrent tumor was pathologically similar despite treatment-associated changes.Awareness of this angiosarcomatous component in gliosarcoma with the hemorrhagic risk is important for both the preoperative diagnosis and surgical management.