A New Synthesis Process of Highly Efficient and Low Toxic Fungicide Difenoconazole

• 作者: He Yongli Tao Yachun Zhou Wei
• 来源期刊: Plant Diseases and Pests(植物病虫害研究:英文版)
• 学科: 化学
• 关键词: DIFENOCONAZOLE SYNTHESIS New process
• 年，卷（期）: pdapzwbchyj,（2）
• 页码范围: 14-15
• 页数: 2页
• 分类号: O62

摘要

A new synthesis method of difenoconazole is studied.Difenoconazole is prepared from m-dichlorobenzene by Friedel Crafts reaction,cyclization,bromination,nucleophilic substitution and etherification.The new process improves the selectivity of the reaction and simplified the pu-rification process.The total yield of this process is 84%,which provides a green and economical synthetic route for industrialization.