Outcomes of Extracorporeal Membrane Oxygenation in Blood Culture Positive Septic Patients

• 作者: Cameron Blazoski Hitoshi Hirose Qiong Yang
• 来源期刊: 心血管外科国际期刊(英文)
• 学科: 医学
• 关键词: Extracorporeal Membrane Oxygenation Shock SEPSIS
• 年，卷（期）: 2020,（8）
• 页码范围: 158-166
• 页数: 9页
• 分类号: R65

摘要

<b><span style="font-family:Verdana;">INTRODUCTION</span></b><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">: Extracorporeal membrane oxygenation (ECMO) is commonly used for refractory cardiac or respiratory failure. There are reported cases of successful use of ECMO in patients with septic shock;however, there is a lack of evidence to prove its overall efficacy. Thus, we conducted this study to analyze the relationship between sepsis and ECMO in our own patients.</span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">METHODS</span></b></span></span><span><span><span style="font-family:;" "=""><span style="font-family:Verdana;">: 305 patients who were placed on ECMO between 2010 and 2020 were identified within an IRB-approved database. Their clinical outcomes were an</span><span><span style="font-family:Verdana;">alyzed with a specific focus on patients who were septic before or during ECMO, defined as a positive blood culture. Group S was composed of patients with a positive blood culture before or during ECMO, while Group N was composed of all patients without a positive blood culture before or during ECMO. The primary outcome compared between groups was </span><span style="font-family:Verdana;">ECMO</span><span style="font-family:Verdana;"> survival rate. </span><b><span style="font-family:Verdana;">RESULTS</span></b><span style="font-family:Verdana;">: Among the 305 patients on ECMO, 58 (19%) were in Group S and 247 (81%) were in Group N. ECMO survival rates were 45% in Group S and 62% in Group N (p = 0.017).</span></span></span></span></span><span><span><span style="font-family:;" "=""> </span></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><b><span style="font-family:Verdana;">CONCLUSION</span></b></span></span><span style="font-family:Verdana;"><span style="font-family:Verdana