Spontaneous Bacterial Peritonitis and Short-Term Prognosis in a Group of Decompensated Cirrhotic Patients in Yaounde: A Cross-Sectional Study

• 作者: Bernadette Ngo Nonga Firmin Ankouane Andoulo Gabin Ulrich Kenfack Hortense Gonsu Kamga Larissa Pessidjo Djomatcho Mathurin Pierre Kowo Nelly Karelle Weyou Noubissi Sylvain Raoul Simeni Njonnou
• 来源期刊: 肠胃病学期刊(英文)
• 学科: 医学
• 关键词: Spontaneous Bacterial Peritonitis Decompensated Liver Cirrhosis Sub-Saharan Africa
• 年，卷（期）: 2020,（8）
• 页码范围: 203-213
• 页数: 11页
• 分类号: R57

摘要

<b style="line-height:1.5;">Introduction:</b><span style="line-height:1.5;"> Spontaneous bacterial peritonitis (SBP) is among the most common infection</span><span style="line-height:1.5;">s</span><span style="line-height:1.5;"> in cirrhotic patients. Data on SBP are rare in Cameroon. This prompted us to carry out this study on patients with decompensated cirrhosis of the liver in Yaounde University Hospital Centre (YUHC). <b>Methods:</b> We carried out a cross-sectional study from December 2015 to June 2016 in three units of YUHC. All patients with decompensated liver cirrhosis were included. Our sampling was consecutive. Diagnosis of cirrhosis was performed, based on clinical, biological and ultrasound criteria. A neutrophil count greater than 250 cell/mm³ in ascites fluid defined an SBP. Data on socio-demography, clinical presentation, and outcomes were collected. <b>Results:</b> We included 34 decompensated cirrhotic patients (15 males). Patients mean age was 57.5</span><span style="line-height:1.5;"> </span><span style="line-height:1.5;">±</span><span style="line-height:1.5;"> </span><span style="line-height:1.5;">2 years (SBP positive: 48.7 ± 21.3 versus without SBP: 59.8 ± 19.5, p</span><span style="line-height:1.5;"> </span><span style="line-height:1.5;">=</span><span style="line-height:1.5;"> </span><span style="line-height:1.5;">0.22). SBP diagnosis was made in 6 (17.7%) patients. Compared to patients with decompensated liver cirrhosis and without SBP, positive SBP patients had a higher pulse rate (p</span><span style="line-height:1.5;"> </span><span style="line-height:1.5;">=</span><span style="line-height:1.5;"> </span><span style="line-height:1.5;">0.002) and respiratory rate (p</span><span style="line-height:1.5;"> </span><span style="line-height:1.5;">=</span><span style="line-height:1.5;"> </span><span style="line-height:1.5;">0.02). The patients with SBP were more likely to present these other clinical features: pulse rate >100 (RR: 4.2, [95% CI: 0.7 </span><span style="line-height: