Imaging Three-Dimensional Microvascular Networks of Brain with Synchrotron Radiation Microangiography

• 来源期刊: 神经科学通报（英文版）
• 年，卷（期）: 2020,（4）
• 页码范围: 331-332
• 页数: 2页
• 语种: 英文

摘要

The adult human brain represents about 2％ of the body weight,yet consumes about 20％ of the body's total energy.A key constituent in meeting this high energy demand is a complex cerebral vascular system.A detailed knowledge of this system is important for understanding the basic principles of cerebral blood flow and its coupling to neural processing and neuropathological alterations in brain diseases.In this issue,Gu and collaborators utilized synchrotron radiation (SR) microangiography to acquire high-resolution (about 5 μm),high-contrast images of the brain tissue of rats under both normal and epileptic seizure conditions without the use of any contrast agent or labeling marker [1].This study demonstrates that SR microangiography can provide systematic and detailed views of cerebrovascular anatomy at the micron level.