Management of hypertension in COVID-19

• 作者: Alastair E Moody Bryce D Beutler Christopher J Rowan Daniel Antwi-Amoabeng Nageshwara Gullapalli Zahara Kanji
• 来源期刊: 世界心脏病学杂志:英文版(电子版)
• 学科: 医学
• 关键词: Angiotensin converting enzyme inhibitor Angiotensin receptor blocker CARVEDILOL Coronavirus disease-19 COVID-19 SARS-CoV-2 VERAPAMIL
• 年，卷（期）: 2020,（5）
• 页码范围: 228-230
• 页数: 3页
• 分类号: R563.1

摘要

The ACE2 receptor plays a central role in severe acute respiratory syndrome coronavirus 2 host cell entry and propagation.It has therefore been postulated that angiotensin converting enzyme inhibitors and angiotensin receptor blockers may upregulate ACE2 expression and thus increase susceptibility to infection.We suggest that alternative anti-hypertensive agents should be preferred among individuals who may be exposed to this increasingly common and potentially lethal virus.