Kyoto classification in patients who developed multiple gastric carcinomas after Helicobacter pylori eradication

• 作者: Akira Toyoshima Kazuhiko Koike Kosuke Sakitani Masatoshi Irokawa Osamu Toyoshima Shuntaro Yoshida Tatsuya Matsuno Tomoharu Yamada Toshihiro Nishizawa Yoshiyuki Takahashi Yousuke Nakai
• 来源期刊: 世界胃肠内镜杂志:英文版(电子版)
• 学科: 医学
• 关键词: Kyoto classification Gastric cancer Helicobacter pylori Eradication therapy METACHRONOUS Intestinal metaplasia
• 年，卷（期）: 2020,（9）
• 页码范围: 276-284
• 页数: 9页
• 分类号: R73

摘要

BACKGROUND Endoscopic Kyoto classification predicts gastric cancer risk;however,the score in the patients with primary gastric cancer after Helicobacter pylori(H.pylori)eradication therapy is unknown.AIM To elucidate the Kyoto classification score in patients with both single gastric cancer and multiple gastric cancers developed after H.pylori eradication.METHODS The endoscopist recorded the Kyoto classification at the endoscope and the Kyoto classification score at the time of the first diagnosis of gastric cancer after H.pylori eradication.The score was compared between single gastric cancer group and multiple gastric cancers group.RESULTS The Kyoto score at the time of diagnosis of 45 cases of gastric cancer after H.pylori eradication was 4.0 points in average.The score was 3.8 points in the single gastric cancer group,and 5.1 points in the multiple gastric cancers group.The multiple group had a significantly higher score than the single group(P=0.016).In the multiple gastric cancers group,all the patients(7/7)had 5 or higher Kyoto score,while in single gastric cancer group,the proportion of patients with a score of 5 or higher was less than half,or 44.7%(17/38).CONCLUSION Patients diagnosed with gastric cancer after H.pylori eradication tended to have advanced gastritis.In particular,in cases of multiple gastric cancers developed after H.pylori eradication,the endoscopic Kyoto classification score tended to be 5 or higher in patients with an open type atrophic gastritis and the intestinal metaplasia extended to the corpus.