The novel Coronavirus disease or COVID-19 is a new contagious, dangerous, and deadly viral/immunological systemic disorder with predominantly respiratory features caused by human infection with SARS-CoV-2, which is rapidly spreading from person-to-person all around the world as a pandemic. If the COVID-19 pandemic is not controlled, and then eradicated, it will probably cause the extinction of the human race in the coming years or decades! It shows the fastest multiple genetic mutation for SARS-CoV-2 in the development of the disease. According to the author of this article, an effective vaccine for SARS-CoV-2 will not be made any time soon or may never be made. If it is made, due to the need to use the vaccine several times a year, the staggering cost of vaccine production, its potentially insufficient effect in preventing COVID-19, its possible side effects, and the complexity of its equitable distribution worldwide, it cannot be a significant success in preventing the COVID-19 pandemic. Hence, the only way to eradicate COVID-19 pandemic is: simultaneous, synchronized, and universal quarantine for at least 40 days for all the people of the planet as staying at home for 99% of them and staying at workplace for another 1%, that because of the need for their key job, they need to be present at work. By applying the COVID-19 Referral System for screening people infected with SARS-CoV-2 and Persian Gulf Criteria for diagnosis of COVID-19, we recommend home isolation for mild cases of COVID-19 and hospitalization in Corona Center for severe cases. Also, along with these, more and more SARS-CoV-2 diagnostic tests should be performed using highly sensitive kits, and the principles of prevention of becoming infected with the SARS-CoV-2 should be followed carefully and as soon as possible. By applying all the above, success in controlling and suppressing the SARS-CoV-2 epidemics is anticipated.