Palladium-catalyzed ortho-C-H silylation of biaryl aldehydes using a transient directing group

• 作者: Bing-Feng Shi Gang Liao Hao-Ming Chen Qi-Jun Yao Yong-Jie Wu
• 来源期刊: 中国科学:化学（英文版）
• 年，卷（期）: 2020,（7）
• 页码范围: 875-880
• 页数: 6页
• 语种: 英文

摘要

A strategy for Pd-catalyzed ortho-C-H silylation of biaryl aldehydes enabled by a transient auxiliary is presented.This protocol provides a broad range ofortho-silylated biaryl aldehydes in good yields.The silyl moiety can be further functionalized under mild conditions,rendering the silylated products useful building blocks.Notably,this protocol also offers an opportunity to establish a platform for expeditious synthesis of structurally diverse axially chiral biaryl aldehydes via sequential atroposelective interannular C-H functionalization/intraanular C-H silylation.

作者信息

序号	姓名	单位	发文数	被引次数	H指数	G指数
1	Yong-Jie Wu		1	0	0.0	0.0
2	Qi-Jun Yao		1	0	0.0	0.0
3	Hao-Ming Chen		1	0	0.0	0.0
4	Gang Liao		1	0	0.0	0.0
5	Bing-Feng Shi		1	0	0.0	0.0