Hearing loss and cognitive decline among older adults with atrial fibrillation:the SAGE-AF study
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摘要:
Objective To examine the association between hearing loss and cognitive fimction cross-sectionally and prospectively among older adults with atrial fibrillation (AF).Methods Patients with AF ≥ 65-year-old (n =1244) in the SAGE (Systematic Assessment of Geriatric Elements)-AF study were recruited from five internal medicine or cardiology clinics in Massachusetts and Georgia.Hearing was assessed by a structured questionnaire at baseline.Cognitive function was assessed by Montreal Cognitive Assessment (MoCA) at baseline and one year.Cognitive impairment was defined as score ≤ 23 on the MoCA.The associations between hearing loss and cognitive function were examined by multivariable adjusted logistic regression.Results Participants with hearing loss (n =451,36%) were older,more likely to be male,and have depressive symptoms than patients without hearing loss.At baseline,528 (42%) participants were cognitively impaired.Individuals with hearing loss were significantly more likely to have cognitive impairment at baseline[adjusted odds ratio (OR) =1.37,95% confidence interval (CI): 1.05-1.81].Among the 662 participants who did not have cognitive impairment at baseline and attended the one-year follow-up visit,106 (16%) developed incident cognitive impairment.Individuals with,versus those without,hearing loss were significantly more likely to develop incident cognitive impairment at one year (adjusted OR =1.68,95% CI: 1.07-2.64).Conclusions Hearing loss is a prevalent but under-recognized factor associated with cognitive impairment in patients with AF.Assessment for hearing loss may be indicated among these patients to identify individuals at high-risk for adverse outcomes.