Editorial of Special Issue on Drug Metabolism and Disposition in Diseases

• 来源期刊: 药学学报（英文版）
• 年，卷（期）: 2020,（1）
• 页码范围: 1-2
• 页数: 2页
• 语种: 英文

摘要

I am very happy to present you with a Thematic Issue on "Drug Metabolism and Disposition in Diseases". Drug metabolism and disposition are essential to both drug therapy and drug safety.Besides genetic and environmental factors,it has been more and more appreciated that disease and physiological states of the patients can also impact on drug metabolism and disposition.On the other hand,the expression or activity of drug-metabolizing enzymes and transporters can have profound effect on the clinical outcome of diseases.In 2016,I edited a book of a similar title Drug Metabolism in Diseases (Academic Press/Elsevier 2016;ISBN:9780128029497) that was dedicated to disease-drug interactions.The diseases and physiological conditions covered in the 2016 Elsevier book included liver and kidney diseases,inflammation,diabetes,pregnancy,and pediatric populations.However,several other areas were left uncovered,which motivated me to edit a Thematic Issue that continues focusing on the disease-drug interactions.